Our free MLB parlay picks are out for Wednesday, September 21st, 2022! Make sure you check our expert MLB parlay picks before the action kicks off.
New York Mets @ Milwaukee Brewers – 2:10PM ET
My first pick for this game is for the New York Mets starting pitcher Taijuan Walker. He comes into this game with a record of 12-4 through their first 26 appearances of the 2022 Major League Baseball season. He is currently averaging around four and half innings pitched and I have him going over his total outs in this game.
My second pick for this game is for the New York Mets to pick up the victory over the Milwaukee Brewers in the third and final game of their three game series. The New York Mets have already won the first two games of this series and I look for them to complete the sweep here in game number three on Wednesday afternoon.
MLB Parlay Pick 
Walker Over Outs & Mets ML
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Cleveland Guardians @ Chicago White Sox – 8:10PM ET
My first pick for this game is for the Cleveland Guardians starting pitcher Triston McKenzie. He is putting together a great year for the American League Central leading Guardians, as he comes into this game with a record of 10-11 through his first 28 appearances of the 2022 Major League Baseball season. He is currently averaging around six and half innings pitched and I have him going over his total outs in this game.
My second pick for this game is for the Cleveland Guardians to pick up the victory over the Chicago White Sox in the second game of their three game series on Wednesday evening. In game number one of the series on Tuesday night, the Guardians picked up a massive victory in extra innings to extend their lead in the American League Central division to five games. They also officially clinched the season series over the White Sox which gives them the tiebreaker. I look for them to add another win on Wednesday.
MLB Parlay Pick
McKenzie Over Outs & Guardians ML
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San Francisco Giants @ Colorado Rockies – 8:40PM ET
My first pick for this game is for the San Francisco Giants starting pitcher Logan Webb. He comes into this game with a record of 13-9 through his first 30 appearances of the 2022 Major League Baseball season. He is currently averaging around six innings pitched and I have him going over his total outs in this game.
My second pick for this game is for the San Francisco Giants to pick up the victory over their National League West division rivals, the Colorado Rockies, in the third game of their four game weekday series. The San Francisco Giants have already won the first two games of this series and I look for them to officially clinch the series here in game number three on Wednesday night.
MLB Parlay Pick
Webb Over Outs & Giants ML
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Seattle Mariners @ Oakland Athletics – 9:40PM ET
My first pick for this game is for the Seattle Mariners starting pitcher Robbie Ray. He is putting together a solid season for the Mariners this year as he comes into this game with a record of 12-10 through his first 29 appearances of the 2022 Major League Baseball season. He is currently averaging around six innings pitched and I have him going over his total outs in this game.
My second pick for this game is for the Seattle Mariners to pick up the victory over their American League West division rivals, the Oakland Athletics, in the second game of their three game series. In game one of the series on Tuesday evening the Oakland Athletics upset the Seattle Mariners but I expect the Mariners to bounce back here in game number two.
MLB Parlay Pick
Ray Over Outs & Mariners ML
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St.Louis Cardinals @ San Diego Padres – 9:40PM ET
My first pick for this game is for the St.Louis Cardinals starting pitcher Miles Mikolas. He comes into this game with a record of 11-12 through his first 30 appearances of the 2022 Major League Baseball season. He is currently averaging around six innings pitched and I have him going over his total outs in this game.
My second pick for this game is for the St.Louis Cardinals to pick up the victory over the San Diego Padres in the second game of their three game series here on Tuesday evening. With Mikolas on the mound I look for the Cardinals to have the clear advantage in this game as they look to make their playoff push a reality as the final week of the season quickly approaches.
MLB Parlay Pick
Mikolas Over Outs & Cardinals ML
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